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KMID : 0363320160370010109
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Journal of Korean Oriental Internal Medicine
2016 Volume.37 No. 1 p.109 ~ p.134
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Analysis of Recent Clinical Studies to Establish Korean Herbal Medicine Clinical Trial Guidelines for the Common Cold
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Kim Kwan-Il
Lee Ho-Jung
Lee Beom-Jun
Jung Doo-Young
Jung Sung-Ki
Lee Jun-Hee
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Abstract
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Objectives: The aim of this study was to help develop a guideline for the common cold. We searched recent clinical studies of the common cold in Western medicine and reviewed their objectives, inclusion and exclusion criteria, primary outcome, secondary outcome, and assessment tools to establish evidenced-based guideline.
Methods: We searched electronic databases (Cochrane Library, MEDLINE, EMBASE) to identify eligible randomized controlled trials (RCTs) about the common cold for the last 10 years. We included 29 RCTs and showed their research summary via their objectives, participants, interventions, control, treatment duration, and results. We also analyzed the definition of the common cold presented in the article, inclusion and exclusion criteria, primary and secondary outcomes, and assessment tools.
Results: We reported the aforementioned areas in detail. At first, the definition of the common cold was confused across
the articles. Second, herbal medication clinical trials for the common cold have been extensively studied recently. Third, the eligibility criteria frequently included the Jackson Symptom score. Fourth, validated assessment tools (i.e., the Wisconsin Upper Respiratory Symptom Survey-21) have only been used in a few recent studies.
Conclusions: Our research will be helpful to establish Korean herbal medicine clinical trial guidelines for the common cold.
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KEYWORD
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common cold, randomized controlled trial, review
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